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Eukaryotic Gene Expression NPTEL

Online Free Online Course by  World Mentoring Academy
Online / Free Online Course

Details

The objective of this course is to expose the viewer to basic aspects of regulation of gene expression in eukaryotes and explain the benefits that have accrued out of basic research in this area. The course is organized such that the viewer will learn not only gain knowledge on the molecular mechanisms involved in eukaryotic gene regulation but also will appreciate the benefits that have accrued through the exploitation of knowledge gained from the basic research, primarily in the areas of disease diagnosis and their prevention, agriculture etc.

Resources: OpenCourseware from NPTEL (India), Sheridan College, MIT, UC Berkeley, Stanford & many other of the World's finest University's

Language: English

Professors: Michael Williams

Units: 40

Lesson content
  • Mod-01 Lec-01 Eukaryotic RNA polymerases and basal transcription factors  
  • Mod-01 Lec-02 Diversity in core promoter elements  
  • Mod-01 Lec-03 Diversity in general transcription factors  
  • Mod-01 Lec-04 Proximal & Distal Promoter Elements,Enhancers and Silencers, Gene-specific Regulators  
  • Mod-02 Lec-05 Transcription factors : DNA binding domains  
  • Mod-02 Lec-06 Transcription factors: transcription activation domains  
  • Mod-03 Lec-07 Role of chromatin in eukaryotic gene regulation  
  • Mod-03 Lec-08 Role of histones in eukaryotic gene regulation  
  • Mod-03 Lec-09 Role of DNA methylation in eukaryotic gene regulation  
  • Mod-03 Lec-10 Chromatin remodelling & gene regulation  
  • Mod-04 Lec-11 Co-transcriptional and post-transcriptional modifications of pre messenger RNA-I  
  • Mod-04 Lec-12 Co-transcriptional and post-transcriptional modifications of pre messenger RNA-II  
  • Mod-04 Lec-13 Regulation of RNA Pol I transcription  
  • Mod-04 Lec-14 Regulation of tRNA and 5s rRNA synthesis by RNA Polymerase III  
  • Mod-05 Lec-15 Signal Transduction Pathways - Introduction  
  • Mod-05 Lec-16 Regulation of gene expression by cyclicAMP  
  • Mod-05 Lec-17 Regulation of gene expression by second messengers other than cAMP  
  • Mod-05 Lec-18 Regulation of gene expression by Protein Kinase C  
  • Mod-05 Lec-19 Regulation of gene expression by Growth factors  
  • Mod-05 Lec-20 Regulation of gene expression by cytokines  
  • Mod-06 Lec-21 Regulation of gene expression by steroid hormones  
  • Mod-06 Lec-22 Regulation of gene expression by type II nuclear receptors  
  • Mod-06 Lec-23 Mechanism of transcriptional activation by nuclear receptors  
  • Mod-07 Lec-24 Gene Regulation during Drosophila Development  
  • Mod-07 Lec-25 Signal transduction pathways involved in embryonic development  
  • Mod-07 Lec-26 Homeotic genes  
  • Mod-07 Lec-27 Epigenetic regulation of gene expression during development  
  • Mod-07 Lec-28 Embryonic stem cells and Transcription factor-mediated epigenetic reprogramming  
  • Mod-08 Lec-29 Cloning and Expression vectors  
  • Mod-08 Lec-30 Eukaryotic protein expression systems - I  
  • Mod-08 Lec-31 Eukaryotic protein expression systems - II  
  • Mod-08 Lec-32 Eukaryotic protein expression systems-III  
  • Mod-09 Lec-33 Human Gene Therapy  
  • Mod-09 Lec-34 DNA vaccines  
  • Mod-09 Lec-35 Transgenic animals  
  • Mod-09 Lec-36 Transgenic plants  
  • Mod-09 Lec-37 Knockout mice  
  • Mod-10 Lec-38 Regulation of Eukaryotic Gene Expression by Small RNAs (RNA Interference, RNAi)  
  • Mod-10 Lec-39 Genomics & Proteomics  
  • Mod-10 Lec-40 Metabolic Engineering & Synthetic Biology  
- See more at: http://worldmentoringacademy.com/www/index.php?ctg=lesson_info&lessons_ID=907#sthash.PR40PPGA.dpuf
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